A new research has revealed that increase in intake of Vitamin D is likely to help in the treatment of patients suffering from multiple sclerosis (MS). The autoimmune disorder has adverse impacts on the brain and spinal cord. Vitamin D has come up as an economical and simple cure for the problem. The study states that increased Vitamin D might be instrumental in normalizing the hyperactive immune response.
"More research is needed to confirm these findings with larger groups of people and to help us understand the mechanisms for these effects, but the results are promising," said Peter Calabresi, Johns Hopkins Multiple Sclerosis Center’s D and professor at the Johns Hopkins University School of Medicine.
Reduction in vitamin D levels is associated with the higher chances of developing the disorder. Patients with both MS and low Vitamin D levels have greater risk of disability and increased disease activity. The researchers performed the study on 40 relapsing-remitting MS patients. Some were daily given 10,400 international units, while others were given 800 international units of vitamin D supplements for six months.
The researchers observed vitamin D levels and the affect on the immune system's T cells at the beginning of the study and then after three and six months. T cells play an important part in MS. Suggested Vitamin D optimal levels in MS patients is 40-60 nanogrammes per millilitre (ng/ml). Participants with higher Vitamin D intake achieved the optimal levels and had lower percentage of inflammatory T cells, particularly IL-17+CD4+ and CD161+CD4+.